## Abstract 4‐1BBL^–/–^ mice have a defect in recall CD8^+^ T cell responses to viruses, whereas CD4^+^ T cell responses to virus are unimpaired in these mice. In contrast, both CD4^+^ and CD8^+^ T cells respond to 4‐1BB ligand (4‐1BBL) __in vitro__. To clarify the role of 4‐1BB/4‐1BBL in CD4^+^ ve
Kinetics of CD8+ effector T cell responses and induced CD4+ regulatory T cell responses during Friend retrovirus infection
✍ Scribed by Gennadiy Zelinskyy; Anke R. M. Kraft; Simone Schimmer; Tanja Arndt; Ulf Dittmer
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 549 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract To evaluate the __in vivo__ effect of immunosuppressive glucocorticoids on CD4^+^CD25^+^ T regulatory cells, we injected dexamethasone (Dex) into BALB/c mice. Administrationof Dex enhanced the proportion of CD4^+^CD25^+^ cells and the ratio of CD4^+^CD25^+^ cells to CD4^+^CD25^–^ cells
## CD4 and CD8: modulators of T-cell receptor recognition of antigen and of immune responses? Rose Zamoyska The response of T cells to antigen involves the participation of a number of distinct receptor-ligand engagements. The major players in the recognition of complexes of major histocompatibili
## Abstract The magnitude and quality of T cell responses generated when Ag is targeted to receptors on DC is influenced by both the specific receptor targeted and its distribution among DC subsets. Here we examine the targeting of the model Ag OVA to potential DC targets, including CD11c, CD205, M