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Kinetics of Acetaminophen Glucuronidation by UDP-Glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential Implications in Acetaminophen−Induced Hepatotoxicity

✍ Scribed by Mutlib, Abdul E.; Goosen, Theunis C.; Bauman, Jonathan N.; Williams, J. Andrew; Kulkarni, Shaila; Kostrubsky, Seva


Book ID
118174478
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
340 KB
Volume
19
Category
Article
ISSN
0893-228X

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Stereoselective metabolism of propranolo
✍ Lushan Yu; Minrong Qian; Yao Liu; Tongwei Yao; Su Zeng 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 293 KB

## Abstract Stereoselective metabolism of propranolol side‐chain glucuronidation was studied for two recombinant human uridine diphosphate glucuronosyltransferases (UGTs), UGT1A9 and UGT2B7. The __S__‐ and __R__‐propranolol side‐chain glucuronides produced in the incubation mixtures were assayed si