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Kinetics and concentration effects of TPA-induced differentiation of cultured human neuroblastoma cells

✍ Scribed by Sven Påhlman; Aino-Inkeri Ruusala; Lars Abrahamsson; Lena Odelstad; Kenneth Nilsson

Book ID
113210252
Publisher
Elsevier Science
Year
1983
Weight
422 KB
Volume
12
Category
Article
ISSN
0045-6039

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20500 h o , Finland (1.H.I SH-SY5Y human neuroblastoma cells can be induced to differentiate into a neuronal phenotype by treatment with 12-O-tetradecanoylphorbol-13-acctatc UPA). In other cell systems, TPA treatment frequently leads to down-regulation of protein kinase C (PKC). However, we now rep