Kinetically controlled total syntheses of dl-trachelanthamidine and dl-isoretronecanol
โ Scribed by Danishefsky, Samuel; McKee, Robert; Singh, R. K.
- Book ID
- 121341558
- Publisher
- American Chemical Society
- Year
- 1977
- Tongue
- English
- Weight
- 836 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0002-7863
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
After we published the intramolecular cyclization of the oxindole iminoether,l Scott made a proposal claiming an important role of the oxindole alkaloid in the biosynthesis of various indole alkaloids. 2 Thus, attention was drawn to synthesize the pentacyclic oxindole alkaloids which are abundant in
We report herein the total synthe.ses of 2-deoxy-DL-and L-rlboses. As Illustrated in the following scheme, the Reformatsky reaction of ethyl bromoaoetate with aoroleln afforded the p-hydroxy eater (I) in a yield of 40-502, whloh was hydrolysed by means of aqueous potassium hydroxide to give the DL-a