Kinetic study of microwave-assisted Wittig reaction of stabilised ylides with aromatic aldehydes
β Scribed by Sara Frattini; Monica Quai; Enzo Cereda
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 57 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The Wittig reaction of a pool of stabilised ylides and aromatic aldehydes was carried out in a microwave oven. Only a few minutes were needed for high conversion rates under microwave heating in comparison to hour time with traditional methods.
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## Abstract For Abstract see ChemInform Abstract in Full Text.
The reaction of aldehydes with oxido ylides shows a dramatic dependence of alkene stereochemistry on the distance between oxygen and phosphorus atoms; ylides with proximal 0 and P atoms favor production of g alkenes. The high r stereoselectivity with r-oxido ylides is not mainly attributable to intr