Kinetic studies of inverse electron demand Diels–Alder reactions (iEDDA) of norbornenes and 3,6-dipyridin-2-yl-1,2,4,5-tetrazine
✍ Scribed by Knall, Astrid-Caroline; Hollauf, Manuel; Slugovc, Christian
- Book ID
- 125794566
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- French
- Weight
- 360 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0040-4039
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Inverse Electron Demand Diels-Alder Reactions of 3,6-Dichloro-[1,2,4,5]tetrazine. -Tetrazine (I) is used as an azadiene equivalent for inverse electron demand Diels -Alder reactions with alkynes and alkenes to give functionalized dichloropyridazines, e.g. (III), (V), and (VII). -(SPAREY, T.
The selective preparation of 3-methoxy-6-methylthio-l,2,4,5-tetrazine (2) and 3,6-dimethoxy-l,2,4,5-tetrazine (3) from 3,6°bis(methylthio)-l,2,4,5-tetrazine (1) is described. A preliminary investigation into the participation of 2 in [4+2] cycloaddition reactions with electron rich and neutral dieno