Kinetic studies of inhibition of estradiol 2- and 16α-hydroxylases with 17α-ethynyl and 17β-cyano steroids: Preferential inhibition of the 16α-hydroxylase
✍ Scribed by Numazawa Mitsuteru; Satoh Satoshi
- Book ID
- 116007349
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 714 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0022-4731
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📜 SIMILAR VOLUMES
We have discovered that chlorine in 3~-acetoxy-17-chloro-16-formylandrosta-5,16-diene (1) can be smoothly displaced by nitrogen heterocyclic nucleophiles (her) to give heretofore unknown 17-substituted-A t6 steroids in high yields (73-92%). This enabled us to synthesize novel 3~-hydroxy-17-(1H-1,2,4
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