Kinetic resolution of aromatic β-amino acids by ω-transaminase
✍ Scribed by Bea, Han-Seop; Park, Hye-Jeong; Lee, Sang-Hyeup; Yun, Hyungdon
- Book ID
- 121420262
- Publisher
- Royal Society of Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 637 KB
- Volume
- 47
- Category
- Article
- ISSN
- 1359-7345
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📜 SIMILAR VOLUMES
## Abstract We describe a simple and efficient enzymatic tandem reaction for the preparation of enantiomerically pure __β__‐phenylalanine and its analogues from the corresponding racemates. In this process, phenylalanine aminomutase (PAM) catalyzes the stereoselective isomerization of (__R__)‐__β__
## Abstract **Access to enantiopure β‐amino acids**: β‐Aminopeptidases are hydrolases that possess the unique ability to cleave N‐terminal β‐amino acids from peptides and amides. Hydrolysis of racemic β‐amino acid amides catalyzed by these enzymes displays enantioselectivity with strong preference