Kinetic properties of arachidonoyl-coenzyme A synthetase in rat brain microsomes
β Scribed by T.Sanjeeva Reddy; Nicolas G. Bazan
- Book ID
- 115705692
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 608 KB
- Volume
- 226
- Category
- Article
- ISSN
- 0003-9861
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Synthesis of arachidonoyl CoA and docosahexaenoyl CoA in homogenates and microsomes from cerebrum, cerebellum, and brain stem and in synaptic plasma membranes from cerebrum of control rats and rats undergoing bicuculline-induced status epilepticus were studied. Arachidonoyl CoA synthesis was 3-5 tim
Long-chain acyl-CoA synthetase (EC 6.2.1.3), an enzyme(s) that activates fatty acids prior to incorporation into phospholipids and other substances, has been detected in highly purified myelin from rat brain stem. The high levels relative to microsomes (11% and 15% for oleate and arachidonate, respe