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Kinetic Properties of a MNB/DYRK1A Mutant Suitable for the Elucidation of Biochemical Pathways †

✍ Scribed by Adayev, Tatyana; Chen-Hwang, Mo-Chou; Murakami, Noriko; Wegiel, Jerzy; Hwang, Yu-Wen


Book ID
126918051
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
172 KB
Volume
45
Category
Article
ISSN
0006-2960

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Labeled glycerol is a widely used biochemical probe to investigate biosynthetic pathways. A highly efficient synthesis of [1-13 C, 18 O]-and [1-13 C, 2 H 2 ]-glycerol is described in which the 13 C label is introduced using cyanide. The 18 O label was introduced by a Pinner synthesis and reduction o