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Kinetic mechanisms of the forward and reverse pp60c-src tyrosine kinase reactions

✍ Scribed by Boerner, Renee J.; Barker, Sean C.; Knight, Wilson B.


Book ID
127382872
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
546 KB
Volume
34
Category
Article
ISSN
0006-2960

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Conformational searches on three closely related pp60 c-src protein tyrosine kinase inhibitors of varying potencies were performed to determine a structural basis for their activity. The first was a linear peptide (PDNEYAFFQf), the second its 10-membered cyclic analogue, and the third a cyclic analo