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Kinetic determination of sotalol by oxidation with sodium vanadate

✍ Scribed by Salah M. Sultan; A.M. Bukhari; Herman Perzanowski


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
235 KB
Volume
8
Category
Article
ISSN
0731-7085

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✦ Synopsis


A kinetic method is described for the determination of sotalol. The method uses 0.033 M sodium vanadate to oxidize sotalol in 4 M sulphuric acid. The solution is heated at 90 degrees C and the absorbance is measured at 750 nm at a fixed time of 30 min. The concentration (c) of sotalol is calculated from the absorbance (A) by the equation: A = 0.04 + 0.0015625 c.


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