Kinetic aspects of ultrasound-accelerated lipase catalyzed acetylation and optimal synthesis of 4′-acetoxyresveratrol
✍ Scribed by Kuo, Chia-Hung; Hsiao, Fang-Wen; Chen, Jiann-Hwa; Hsieh, Chang-Wei; Liu, Yung-Chuan; Shieh, Chwen-Jen
- Book ID
- 118502785
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 694 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1350-4177
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BACKGROUND: Optically pure amines are used in the fine chemical industry as resolving agents, chiral auxiliaries, and chiral synthetic building blocks for pharmaceuticals as well as agrochemicals. Lipase-catalyzed kinetic resolution of (±)-1phenylethylamine with ethyl acetate as an acyl donor was ac
The lipase-catalyzed acetylation of a broad spectrum of configurations of the 2-hydroxy acids 1 were assigned by comparison of the gas-chromatographic data with that of racemic 2-hydroxy acids 1 to their 2-acetoxy acids 2 was shown to proceed with high enantioselectivity. Thus, the literature-known