✦ LIBER ✦

Kinetic and biochemical analysis of carrier-mediated efflux of drugs through the blood–brain and blood–cerebrospinal fluid barriers: importance in the drug delivery to the brain

✍ Scribed by Yuichi Sugiyama; Hiroyuki Kusuhara; Hiroshi Suzuki

Book ID: 114163742
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 150 KB
Volume: 62
Category: Article
ISSN: 0168-3659
DOI: 10.1016/s0168-3659(99)00036-x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Contribution of Carrier-Mediated Transpo

Contribution of Carrier-Mediated Transport Systems to the Blood–Brain Barrier as a Supporting and Protecting Interface for the Brain; Importance for CNS Drug Discovery and Development

✍ Sumio Ohtsuki; Tetsuya Terasaki 📂 Article 📅 2007 🏛 Springer US 🌐 English ⚖ 599 KB

Evaluation of drug efflux transporter li

Evaluation of drug efflux transporter liabilities of darifenacin in cell culture models of the blood–brain and blood–ocular barriers

✍ Donald W. Miller; Martha Hinton; Fang Chen 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 232 KB

## Abstract ## Aims The objective of the present study was to evaluate drug efflux transporter interactions of darifenacin and examine the impact of such transporter interactions on darifenacin permeability in an __in vitro__ model of the blood–brain barrier (BBB) and blood–ocular barrier (BOB).

The transport of the anti-HIV drug, 2′,3

The transport of the anti-HIV drug, 2′,3′-didehydro-3′-deoxythymidine (D4T), across the blood-brain and blood-cerebrospinal fluid barriers

✍ Sarah A Thomas; Malcolm B Segal 📂 Article 📅 1998 🏛 Nature Publishing Group 🌐 English ⚖ 288 KB

Kinetic analysis of [36Cl]-, [22Na]- and

Kinetic analysis of [36Cl]-, [22Na]- and [3H]mannitol uptake into the in vivo choroid plexus-cerebrospinal fluid brain system: Ontogeny of the blood-brain and blood-CSF barriers

✍ Quentin R. Smith; Dixon M. Woodbury; Conrad E. Johanson 📂 Article 📅 1982 🏛 Elsevier Science 🌐 English ⚖ 966 KB

Drug transport to the brain: comparison

Drug transport to the brain: comparison between in vitro and in vivo models of the blood-brain barrier

✍ M.P. Dehouck; B. Dehouck; C. Schluep; M. Lemaire; R. Cecchelli 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 791 KB

Inhibition of P-Glycoprotein: Rapid Asse

Inhibition of P-Glycoprotein: Rapid Assessment of Its Implication in Blood-Brain Barrier Integrity and Drug Transport to the Brain by an In Vitro Model of the Blood-Brain Barrier

✍ Laurence Fenart; Valeric Buée-Scherrer; Laurence Descamps; Christian Duhem; Mari 📂 Article 📅 1998 🏛 Springer US 🌐 English ⚖ 782 KB