Kinetic analysis of L-lysine production by a fluoropyruvate sensitive mutant ofB.lactofermentum

✍ Scribed by B. Satiawihardja; R. G. Cail; P. L. Rogers

• Book ID: 104637554
• Publisher: Springer Netherlands
• Year: 1993
• Tongue: English
• Weight: 357 KB
• Volume: 15
• Category: Article
• ISSN: 0141-5492
• DOI: 10.1007/bf00138543

✦ Synopsis

The kinetics of L-lysine production by a fluoropyruvate sensitive (FPs) mutant of B.Zuctofennenrum have been analysed in batch and continuous culture. Under optimal conditions (viz. T = 30°C, pH = 7.0, DO = 10% air saturation) it was established that the initial phosphate level could be used to extend the batch culture to give an L-lysine.HCl concentration of 68.0 g./l and a yield of 0.43 g/g. In continuous culture the yield increased at low dilution rates under conditions similar to those for extended batch culture.