Aqueous-Mediated N-Alkylation of Amines.
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Chingakham B. Singh; Veerababurao Kavala; Akshaya K. Samal; Bhisma K. Patel
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Article
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2007
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John Wiley and Sons
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## N-Alkylation O 0268 Aqueous-Mediated N-Alkylation of Amines. -The alkylation of primary amines with benzyl, alkyl, and allyl bromides or chlorides in the presence of NaHCO 3 in an aqueous medium containing a surfactant gives access to secondary and tertiary amines. The method avoids the use of