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Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts

✍ Scribed by Julie A Wickenden, Christine J Watson

Book ID
120699718
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
391 KB
Volume
12
Category
Article
ISSN
1465-5411

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O besity not only results in increased incidence but also leads to poor prognosis of many cancers. The increased cancer incidence in obesity is accounted for by the activation of cellular signal pathways which are carcinogenic such as Src/PI3K/Akt pathway [Chen, 2008; Huang and Chen, 2009b]. However