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Key signalling nodes in mammary gland development and cancer. Mitogen-activated protein kinase signalling in experimental models of breast cancer progression and in mammary gland development

✍ Scribed by Jacqueline Whyte, Orla Bergin, Alessandro Bianchi, Sara McNally…

Book ID
120699549
Publisher
BioMed Central
Year
2009
Tongue
English
Weight
112 KB
Volume
11
Category
Article
ISSN
1465-5411

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Protein kinases, the enzymes responsible for phosphorylation of a wide variety of proteins, are the largest class of genes known to regulate growth, development, and neoplastic transformation of mammary gland. Mammary gland growth and maturation consist of a series of highly ordered events involving