✦ LIBER ✦

Key Building Blocks of Natural Product Biosynthesis and Their Significance in Chemistry and Medicine

✍ Scribed by Prof. Dr. Burchard Franck

Book ID: 102726101
Publisher: John Wiley and Sons
Year: 1979
Tongue: English
Weight: 973 KB
Volume: 18
Category: Article
ISSN: 0044-8249
DOI: 10.1002/anie.197904291

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The principle features of the biosynthesis of natural products have been elucidated during the past thirty years by the use of isotopic methods. It was discovered that large groups of natural products originate from the same biosynthetic precursor—the key building block. The conversion of key building blocks into biologically active natural products serves as a model for the development of more efficient syntheses in chemistry. In medicine, information about key building blocks permits the elucidation and therapy of metabolic diseases.

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