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Ketanserin analogs: structure-affinity relationships for 5-HT2 and 5-HT1C serotonin receptor binding

โœ Scribed by Ismaiel, Abd; Ingher, Stacy P.; Teitler, M.; Glennon, Richard A.; Herndon, Jeff L.


Book ID
111671743
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
977 KB
Volume
35
Category
Article
ISSN
0022-2623

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ChemInform Abstract: Simplified Analogue
โœ F. CLAUDI; L. SCOCCIA; G. GIORGIONI; G. MARUCCI; A. DI STEFANO; S. GESSI; A. SIN ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 2 views

Simplified Analogues of Ritanserin and Their Affinity at 5-HT 2A , 5-HT 2B , and 5-HT 2C Serotonin Receptors. -A variety of derivatives of 4-[bis(4-fluorophenyl)methylene]piperidine (I) are synthesized and evaluated for their affinity at 5-HT serotonin receptors. The compounds (I) show lower binding