Kennedy's disease: clinical and molecular study of two Italian families
β Scribed by D. Pareyson; B. Castellotti; S. Botti; C. A. Defanti; C. Gellera; F. Taroni; A. Sghirlanzoni
- Publisher
- Springer Milan
- Year
- 1995
- Tongue
- English
- Weight
- 376 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1590-1874
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The clinical features of familial Parkinson's disease (PD) were investigated by examining the families of 20 British probands who were selected on the basis of having clinically typical PD and at least one affected relative. Forty-nine secondary cases were identified. These subjects were clinically
## Abstract Data on the familial aggregation of Parkinson's disease (PD) remain conflicting. We conducted a historical cohort study of 1,001 firstβdegree relatives of 162 probands with PD and of 851 relatives of 147 control probands representative of the population of Olmsted County, Minnesota (fro
## Abstract A novel __SPG4__ 906delT frameβshift mutation in exon 6 was identified in a large Italian family with an autosomal dominant form of hereditary spastic paraplegia (ADHSP). Intrafamilial phenotypic variations observed in the pedigree included spasticity and additional clinical features, s