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KARYOTYPIC CONVERSION IN Ph1-POSITIVE CHRONIC MYELOID LEUKÆMIA WITH COMBINATION CHEMOTHERAPY

✍ Scribed by Sharp, J.C; Joyner, M.V; Wayne, A.W; Kemp, J; Crofts, M; Birch, A.D.J; Mcarthur, G; Lai, S; Sterndale, H; Williams, Y

Book ID
122002646
Publisher
The Lancet
Year
1979
Tongue
English
Weight
391 KB
Volume
313
Category
Article
ISSN
0140-6736

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Clonal evolution with isodicentric Ph1 c
Clonal evolution with isodicentric Ph1 chromosome in Ph1-positive CML: Karyotypic conversion after bone marrow transplantation
✍ Becher, R. ;�hl, S. ;Schaefer, U. W. ;Wendehorst, E. ;Quiskamp, F. ;Mahmoud, H. 📂 Article 📅 1984 🏛 Springer-Verlag ⚖ 443 KB

Clonal chromosomal evolution was observed in a 16-year-old boy suffering from Ph1-positive CML. An isodicentric Ph1 chromosome appeared 20 weeks after the initial diagnosis. At that time an allogeneic bone marrow transplantation was performed. Thereafter, during an observation period of more than 13