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Extremely Long Duration of Chronic Myeloid Leukaemia with Ph1 Negative and Ph1 Positive Bone Marrow Cells

✍ Scribed by BrandT, L. ;MitelmaN, F. ;PananI, A. ;LenneR, H. C.


Book ID
114788801
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
310 KB
Volume
16
Category
Article
ISSN
0036-553X

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A 23-year-old man developed Ph'-positive chronic myelogenous leukemia in 1966. After two short courses of busulfan not associated with severe myelosuppression, the frequency of Ph'-positive metaphases in his bone marrow was 40%. Over the next eight years, he remained hematologically stable without f