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Kappa-1 opioid receptors of the temporal cortex are preserved in Alzheimer's disease

✍ Scribed by K. B. Mackay; D. Dewar; J. McCulloch


Publisher
Springer
Year
1994
Tongue
English
Weight
804 KB
Volume
7
Category
Article
ISSN
1435-1463

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## Abstract The degradation of aberrantly phosphorylated tau in neurons plays an important role in the pathogenesis of Alzheimer's disease (AD). hHrd1 is a newly identified ubiquitin ligase involved in the endoplasmic reticulum (ER)‐associated protein degradation. The expression and function of hHr