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KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancer

✍ Scribed by Jung-Jin Park; Yeung Bae Jin; Yoon-Jin Lee; Jae-Seon Lee; Yun-Sil Lee; Young-Gyu Ko; Minyoung Lee


Book ID
115010463
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
935 KB
Volume
12
Category
Article
ISSN
1471-2407

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## Abstract MicroRNAs (miRNAs) are small non‐coding RNAs that regulate the expression of different genes, including genes involved in cancer progression. A functional link between hypoxia, a key feature of the tumor microenvironment, and miRNA expression has been documented. We investigated whether