Between 1981 and 1986 cytogenetic studies of bone marrow and/or blood cells in 139 patients with de novo acute myeloid leukemia (AML) were performed. The overall incidence of chromosomal aberrations was 53%, and this was not significantly influenced by sex, age nor the FAB classification. The aberra
K313dup is a recurrent CEBPA mutation in de novo acute myeloid leukemia (AML)
β Scribed by Maria J. Carnicer; Adriana Lasa; Marcus Buschbeck; Elena Serrano; Maite Carricondo; Salut Brunet; Anna Aventin; Jorge Sierra; Luciano Di Croce; Josep F. Nomdedeu
- Book ID
- 105989176
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 275 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0939-5555
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The cytogenetic findings in acute myeloid leukemia (AML) are a powerful prognostic indicator. Among these abnormalities, the World Health Organization has classified inv(16)(p13q22), which is closely associated with the M4E classification in the French-American-British system, as indicating a good-r
## Abstract Recently, it was shown that t(10;16)(q22;p13) fuses the __MORF__ and __CREBBP__ genes in a case of childhood acute myeloid leukemia (AML) M5a, with a complex karyotype containing other rearrangements. Here, we report a new case with the __MORF__β__CREBBP__ fusion in an 84βyearβold patie