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Juxtamembrane autoinhibition in receptor tyrosine kinases

✍ Scribed by Hubbard, Stevan R.


Book ID
109958148
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
235 KB
Volume
5
Category
Article
ISSN
1471-0072

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Haematopoiesis is controlled by a number of growth factors and cytokines, a number of which act through binding to high-affinity receptor tyrosine kinases (RTKs). Approximately 20 different RTK classes have been identified, all of which share a similar structure that includes a ligand binding extrac