As a result of differential splicing, one subunit of the nuclear factor Y (NF-Y) consists of two major isoforms designated short (NF-YaS) and long (NF-YaL). In proliferating normal human fibroblasts, NF-YaL is by far the more expressed isoform. Surprisingly, NF-YaS was found by immunoblotting to be
Jun: A transcription factor becomes oncogenic
✍ Scribed by Peter K. Vogt
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 487 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
IRF2 is a transcription factor, possessing oncogenic potential, responsible for both the repression of growth-inhibiting genes (interferon) and the activation of cell cycle-regulated genes (histone H4). Surprisingly little is known about the post-translational modification of this factor. In this st
## Lately, Enron subsidicuy Northern Border Pipeline Company has been resisting a m e by Natural Gas Pipe-
## Abstract Expression of BCR/ABL, a constitutively active tyrosine kinase, is a primary event in the pathogenesis of chronic myeloid leukemia (CML) and Ph‐positive acute lymphoblastic leukemia (Ph+ALL). Inhibition of the BCR/ABL kinase activity in the BV173 CML cell line with STI571 resulted in a
Expression of the jun family of transcription factorslproto-oncogenes in lung cancer From recent studies it is now clear that the product of the cellular counterpart of the oncogene jun (Maki et al., 1987) is one of the proteins making up the transcription-factor preparation AP-1 (Angel et al., 198