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Jasisoquinolines A and B, Architecturally New Isoquinolines, from a Marine Sponge Jaspis sp.

✍ Scribed by Imae, Yasufumi; Takada, Kentaro; Murayama, Shuhei; Okada, Shigeru; Ise, Yuji; Matsunaga, Shigeki


Book ID
126300378
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
825 KB
Volume
13
Category
Article
ISSN
1523-7060

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Jaspines A and B: two new cytotoxic sphi
✍ VΓ©ronique Ledroit; CΓ©cile Debitus; Catherine Lavaud; Georges Massiot πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 125 KB

The ethanolic extract of the sponge Jaspis sp. collected in Vanuatu showed cytotoxicity against KB tumour cells (IC 95 =10 mg/ml). A bioassay-guided fractionation led to the isolation of two new cytotoxic sphingosine derivatives, jaspine A and jaspine B. Structures were elucidated by spectroscopic m