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JAK2 V617F/C618R mutation in a patient with polycythemia vera:A case study and review of the literature

✍ Scribed by Jong-Ha Yoo; Tae Sung Park; Ho-Young Maeng; Young-Kyu Sun; Young-Ah Kim; Jeong-Hae Kie; Eun Hae Cho; Jaewoo Song; Kyung-A. Lee; Borum Suh; Jong Rak Choi


Book ID
113513445
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
287 KB
Volume
189
Category
Article
ISSN
0165-4608

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Switch in X-inactivation in a JAK2 V617F
✍ Kalliopi N. Manola; Chryssa Stavropoulou; Vasileios N. Georgakakos; Katerina Zoi πŸ“‚ Article πŸ“… 2007 πŸ› Elsevier Science 🌐 English βš– 389 KB

We report a JAK2 V617F-negative case of polycythemia vera with two acquired balanced X-autosome translocations and no history of previous exposure to chemo/radiotherapy. The patient's first clone carried a novel translocation t(X;15)(q24;q13) as a sole abnormality. The second clone exhibited an addi