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Concomitant presence of JAK2 V617F mutation and BCR-ABL translocation in a pregnant woman with polycythemia vera

โœ Scribed by Gholamreza Toogeh; Shirin Ferdowsi; Fatemeh Naadali; Kamran Alimoghaddam; Ardeshir Ghavamzadeh; Reza Shirkoohi; Seyed H. Ghaffari


Book ID
107577190
Publisher
Springer US
Year
2010
Tongue
English
Weight
237 KB
Volume
28
Category
Article
ISSN
1357-0560

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Switch in X-inactivation in a JAK2 V617F
โœ Kalliopi N. Manola; Chryssa Stavropoulou; Vasileios N. Georgakakos; Katerina Zoi ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 389 KB

We report a JAK2 V617F-negative case of polycythemia vera with two acquired balanced X-autosome translocations and no history of previous exposure to chemo/radiotherapy. The patient's first clone carried a novel translocation t(X;15)(q24;q13) as a sole abnormality. The second clone exhibited an addi