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Ivermectin: concentration-dependent effects on adenosine triphosphatases in adult worms of Onchocerca volvulus

✍ Scribed by E.N Shu; P.O Okonkwo; W.O Batey; J Onyeanusi

Book ID
117007592
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
75 KB
Volume
74
Category
Article
ISSN
0001-706X

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The effects of high-dose ivermectin regi
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✍ Kwablah Awadzi; Simon Kwaku Attah; Ebenezer Thomas Addy; Nicholas Obuobisa Opoku πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 630 KB

Ivermectin, at the standard dose of 150 cLg/kg bodyweight, does not kill the adult worms of Onchocerca volvulus and does not disrupt embryogenesis or spermatogenesis. Repeated standard doses, if maintained, arrest microfilarial production but result in only a mild-to-modest macrofilaricidal effect.