𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Isotype exclusion and transgene down-regulation in immunoglobulin-λ transgenic mice

✍ Scribed by Neuberger, M. S.; Caskey, H. M.; Pettersson, S.; Williams, G. T.; Surani, M. A.

Book ID
109758321
Publisher
Nature Publishing Group
Year
1989
Tongue
English
Weight
386 KB
Volume
338
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Expression level of a transgenic λ2 chai
Expression level of a transgenic λ2 chain results in isotype exclusion and commitment to B1 cells
✍ Holger Engel; Bjarne Bogen; Urs Müller; Jan Andersson; Antonius Rolink; Siegfrie 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 274 KB

Two new Q 2 chain-transgenic mouse lines were established, both of which showed stable transgene expression during aging of the mice. The line L23, which expressed the transgene at low levels, exhibited normal B cell development, antibody responses and serum Ig levels. Most of the B cells in this mo