## Abstract High field high resolution ^13^C NMR spectroscopy allows the quantitative determination of a mixture of the four diastereomers in racemic Ξ±βtocopherol.
Isotopic Labeling for Determination of Enantiomeric Purity by 2 H NMR Spectroscopy
β Scribed by Jackman, Hayley; Marsden, Stephen P.; Shapland, Peter; Barrett, Simon
- Book ID
- 118149126
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 76 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1523-7060
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π SIMILAR VOLUMES
Absolute configuration and enantiomeric purities of some hydroxyketones and diols of spiro[4\_4]nonane and 2,2'-spirobi-indan can be simultaneously determined by use of MTPA derivatives and a lanthanoid shift reagent.
The enantiomeric characterization of methamphetamine is readily accomplished by 'H-NMR analysis of the diastereomers formed by derivatization with 2,3,4,6-tetra-O-acetylcetyl-8-D glucopyranosyl isothiocyanate (GITC). The stereospecific chemical shifts of a host of signals from the GITC moiely provid