Isothiourea-Mediated One-Pot Synthesis of Functionalized Pyridines
β Scribed by Stark, Daniel G.; Morrill, Louis C.; Yeh, Pei-Pei; Slawin, Alexandra M. Z.; O'Riordan, Timothy J. C.; Smith, Andrew D.
- Book ID
- 121868846
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 590 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0044-8249
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π SIMILAR VOLUMES
3-Chloropentane-2,4-dione exists, in solution, almost exclusively as enol tautomer, which undergoes a complex reaction with dialkyi acetylenedicarboxylates and triphenylphasphine to produce alkyl 5,3-diacetyl-2-oxo-3-(triphenyiphosphoranylidene)tetrahydrofuran-4-carboxylates in moderate to fairly hi
## Abstract magnified image 1,8βDiazabicyclo[5.4.0]undecβ7βene (DBU) efficiently catalyzes threeβcomponent oneβpot condensations of aldehyde, malononitrile, and thiophenol to produce highly functionalized pyridines in excellent yield in aqueous ethanol. J. Heterocyclic Chem., **46**, 69 (2009).