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DBU-catalyzed three-component one-pot synthesis of highly functionalized pyridines in aqueous ethanol

✍ Scribed by Ritu Mamgain; Ram Singh; Diwan S. Rawat

Publisher
Journal of Heterocyclic Chemistry
Year
2009
Tongue
English
Weight
76 KB
Volume
46
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

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1,8‐Diazabicyclo[5.4.0]undec‐7‐ene (DBU) efficiently catalyzes three‐component one‐pot condensations of aldehyde, malononitrile, and thiophenol to produce highly functionalized pyridines in excellent yield in aqueous ethanol. J. Heterocyclic Chem., 46, 69 (2009).

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