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Isosorbide dinitrate kinetics and dynamics after intravenous, sublingual, and percutaneous dosing in angina

✍ Scribed by Morrison, R A; Wiegand, U.-W; Jähnchen, E; Höhmann, D; Bechtold, H; Meinertz, T; Fung, H.-L

Book ID
109843250
Publisher
Nature Publishing Group
Year
1983
Tongue
English
Weight
669 KB
Volume
33
Category
Article
ISSN
0009-9236

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Pharmacokinetics of isosorbide dinitrate
Pharmacokinetics of isosorbide dinitrate after intravenous infusion in human subjects
✍ T. Taylor; L. F. Chasseaud; E. Doyle; A. Darragh; D. A. O'Kelly; D. Fitzgerald 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 391 KB 👁 2 views

## Abstract Plasma concentrations of isosorbide dinitrate have been measured after intravenous infusion of drug at a rate of 5·0 mg h^−1^ for 150 min and after single equal oral doses of 12·5 mg of drug in solution to two normal human subjects. During the infusion, uneven plateau concentrations wer