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Isoquinoline quinones. Preparation of saframycin intermediates and a total synthesis of mimosamycin

✍ Scribed by Parker, Kathlyn A.; Casteel, Dee Ann


Book ID
111984542
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
613 KB
Volume
53
Category
Article
ISSN
0022-3263

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Preparation of the "Ziegler key intermediate" 2from lactone 3, readily obtained from hydroxy-O-ionone, was studied. In a first exploratory approach, lactones 11 and 13 were obtained but further transformations aimed at setting the ring junction were unsuccessful due to unexpected rearrangements. Thr