Isolation, enzyme-bound structure, and a
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Sheo B. Singh; Hiranthi Jayasuriya; Kithsiri B. Herath; Chaowei Zhang; John G. O
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Article
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2009
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Elsevier Science
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French
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Inhibition of fatty acid synthesis is emerging as a valuable target for antibacterial agents. Platensimycin and platencin are novel natural products that were reported recently to inhibit the FabF and FabF/FabH condensing enzymes, respectively, present in the fatty acid biosynthetic pathway. Selecti