Isolation of side population cells from gallbladder carcinoma of human being and the expression of ABCG2 gene
β Scribed by Jun Hu; Jian Li; Min Wang; Zhiyong Du; Min Chen; Renyi Qin
- Book ID
- 106314686
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 342 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1610-1979
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Fibroblast growth factors (FGF) constitute a family of at least 9 members which act through high-affinity tyrosine-kinase receptors encoded by 4 distinct genes. In humans, the FGFRl gene is located in chromosomal region 8 ~1 2 . I t s amplification and expression were examined in a panel of I10 brea
## Abstract Drug resistant tumor βsideβpopulations,β enriched in cancer stem cells and identified by reduced accumulation of Hoechst 33342 under ABCG2βmediated efflux, may compromise therapeutic outcome. Sideβpopulation cells have predicted resistance to minor groove ligands, including the DNA topo