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Isolation of human chromosome 21-specific cosmids and their uses in mapping of cosmid contigs on chromosomal subregions

✍ Scribed by De-Xing Hou; Haruo Kishida; Takanori Shimokawa; Eiichi Soeda


Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
755 KB
Volume
39
Category
Article
ISSN
1435-232X

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cDNA libraries are a potential source of DNA probes which can be used to screen for restriction fragment length polymorphisms (RFLPs). This approach had not been exploited until recently; in this and another paper (Balazs et al. 1984) we show that they can be fruitful source for such probes. As an e