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Isolation of hepatitis B surface antigen (HBsAg) by affinity chromatography on antibody-coated immunoadsorbents

✍ Scribed by B. Houwen; A. Goudeau; J. Dankert

Book ID: 118896818
Publisher: Elsevier Science
Year: 1975
Tongue: English
Weight: 566 KB
Volume: 8
Category: Article
ISSN: 0022-1759
DOI: 10.1016/0022-1759(75)90095-2

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## Abstract Small hepatitis B surface antigen (HBsAg) is considered to be the best marker for the diagnosis of Hepatitis B virus infection. However, HBsAg variants with mutations within the “a” determinant may be poorly or not detected by diagnostic assays. Three anti‐HBsAg monoclonal antibodies (6