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Isolation of Chinese hamster cells hyposensitive to ethyl methanesulfonate and their characterization in induction and antagonization of sister-chromatid exchanges

โœ Scribed by Akira Sono; Kengo Sakaguchi

Book ID
113192736
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
895 KB
Volume
129
Category
Article
ISSN
0027-5107

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Although sister-chromatid exchange (SCE) analysis is recognized as an indicator of exposure to DNA-damaging agents, the results of these analyses have been confounded by the use of bromodeoxyuridine (BrdUrd) to differentially label the sister chromatids. Not only does BrdUrd itself induce SCE, it al