Isolation of a polyamine transport defic
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Dan Shao; Lei Xiao; Hyo-Chol Ha; Robert A. Casero Jr.
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Article
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1996
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John Wiley and Sons
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English
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In an effort to study the mechanism underlying the observed phenotype-specific response of human lung cancer cell lines to a polyamine analogue, N1,N12-bis(ethyl)spermine(BESpm), we have isolated a BESpm resistant cell line from the BESpm-sensitive large cell lung carcinoma line NCI H157. The mutant