New pemetrexed-peptide conjugates: synth
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Zsanett Miklán; Erika Orbán; Zoltán Bánóczi; Ferenc Hudecz
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Article
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2011
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John Wiley and Sons
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English
⚖ 184 KB
Pemetrexed (Pem) is a novel antimetabolite type of anticancer drug that demonstrated promising clinical activity in a wide variety of solid tumors, including non‐small cell lung carcinoma and malignant pleural mesothelioma. It inhibits enzymes involved in the folate pathway, for which the presence o