A recent case-control study suggested that modest enlargements of a CAG repeat in the hKCa3 potassium channel may be associated with bipolar disorder. We tried to replicate this result in a UK Caucasian sample of 203 DSM-IV bipolar I disorder patients and 206 controls group-matched for age and sex.
β¦ LIBER β¦
Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: a candidate for schizophrenia and bipolar disorder?
β Scribed by Chandy, K G; Fantino, E; Wittekindt, O; Kalman, K; Tong, L-L; Ho, T-H; Gutman, G A; Crocq, M-A; Ganguli, R; Nimgaonkar, V
- Book ID
- 110058870
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 112 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1359-4184
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## Abstract The possible presence of anticipation in bipolar affective disorder and schizophrenia has led to the hypothesis that repeat expansion mutations could contribute to the genetic etiology of these diseases. Using the repeat expansion detection (RED) assay, we have systematically examined g