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Isolation and Study of Mutants from Mammalian Cells in Culture

✍ Scribed by Irving Lieberman and Peter Ove

Book ID
123671283
Publisher
National Academy of Sciences
Year
1959
Tongue
English
Weight
871 KB
Volume
45
Category
Article
ISSN
0027-8424

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Isolation of mutant mammalian cells alte
Isolation of mutant mammalian cells altered in polyamine transport
✍ Dr. Jean-Louis Mandel; Dr. Wayne F. Flintoff πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 English βš– 677 KB

## Abstract Chinese hamster ovary and rat myoblast cells resistant to the toxic action of methylglyoxal bis guanylhydrazone (MGBG), an antimitotic agent and inhibitor of polyamine synthesis, have been isolated by single step selection. Mutagenesis with ethyl methanesulfonate increases the recovery