๐”– Bobbio Scriptorium
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Isolation and structure of flutimide, a novel endonuclease inhibitor of influenza virus

โœ Scribed by Otto D. Hensens; Michael A. Goetz; Jerrold M. Liesch; Deborah L. Zink; Susan L. Raghoobar; Gregory L. Helms; Sheo B. Singh


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
205 KB
Volume
36
Category
Article
ISSN
0040-4039

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Novel inhibitors of influenza sialidase
โœ Steven L. Sollis; Paul W. Smith; Peter D. Howes; Peter C. Cherry; Richard C. Bet ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 221 KB

N-Propylcarboxamides la,b-3a,b have been synthesised from 2,3-didehydro-2,4-dideoxy-4amino-N-acetylneuraminic acid 4. The tertiary amides 2a,b-3a,b are highly potent but selective inhibitors of influenza A sialidase. The exceptional inhibitory activity of the dipropylamides 3a and 3b against influen