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Isolation and Structure Determination of Malevamide E, a Dolastatin 14 Analogue, from the Marine Cyanobacterium Symploca laete-viridis ⊥

✍ Scribed by Adams, Beatrice; Pörzgen, Peter; Pittman, Emily; Yoshida, Wesley Y.; Westenburg, Hans E.; Horgen, F. David


Book ID
120640356
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
158 KB
Volume
71
Category
Article
ISSN
0163-3864

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A 14-membered macrolide, koshikalide (1), was isolated from the marine cyanobacterium Lyngbya sp., and its planar structure was elucidated by spectroscopic analysis. The relative stereochemistry of C-11 and C-13 was elucidated by NOESY experiments and by an analysis of 1 H-1 H coupling constants. Ko