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Isolation and characterization of yeast mutants blocked in mevalonic acid formation

✍ Scribed by Madeleine Servouse; Nicole Mons; Jean-Louis Baillargeat; Francis Karst


Book ID
115757306
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
441 KB
Volume
123
Category
Article
ISSN
0006-291X

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Isolation and characterization of acid p
✍ M. E. Schweingruber; A. M. Schweingruber; M. E. SchΓΌpbach πŸ“‚ Article πŸ“… 1982 πŸ› Springer-Verlag 🌐 English βš– 868 KB

72 mutants defective in the activity of the cell surface glycoprotein acid phosphatase were isolated and characterized. The mutants map in one genetic locus, phol. Many of them exhibit altered cell morphology. This characteristic cosegregates with acid phosphatase deficiency, implying that phol cont